ESTRO PT 2018

Preoperative C-ion RT

Survival

year

n

treatment

MST 3-yr

5-yr

182

surgery only

20.2m 21% 12%

CONKO-001 98-04

186

surgery+GEM 22.1m 34% 23%

NIRS

03-13

26

CIRT + surgery

61.5m 60% 54%

Overall Survival

Overall Survival by Dose

low dose (n=10) high dose (n=21) ≤31.6GyE (n=10) ≥33.6GyE (n=21)

100

100

All (n=31)

80

surgery (n=26)

80

60

60

5yOS: 62%

40

40

MST: 61.5m, 5yOS: 54%

20

Percent survival 20

Percent survival

0 12 24 36 48 60 72 84 0

0 12 24 36 48 60 72 84 0

Time from C-ion RT (months)

Time from C-ion RT (months)