ESTRO PT 2018

Dose escalation

Dose Level (CIRT ・ GEM) DOSE Week1 Week2 Week3

# of patients

43.2GyE ・ 400mg/m 2

6

43.2-GyE in 12fr

Carbon

Carbon

Carbon

43.2GyE ・ 700mg/m 2

6

↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓

43.2GyE ・ 1000mg/m 2

12

GEM 400-1000mg/m2

G

G

G

45.6GyE ・ 1000mg/m 2

6

48.0GyE ・ 1000mg/m 2

8

50.4GyE ・ 1000mg/m 2

11

52.8GyE ・ 1000mg/m 2

11

55.2GyE ・ 1000mg/m 2

11