ESTRO PT 2018

Biological Challenges that favor Particle Therapy

Radio-sensitivity

Squamous Cell Carcinoma (SCC) (90%) Undifferentiated Carcinoma Lymphoma

+++

++++

Adenocarcinoma

++

Adenoid-cystic carcinoma * , Mucosal Melanoma, Sarcoma

+

* Neutrons RBE: adenoid-cystic carcinoma = 8.0 normal tissues (late effects) = 3 – 3.5