ESTRO PT 2018

CNS Tumors - Natural history

GLIOMA: 80% of primary malignant tumors

WHO I: PILOCYTIC ASTROCYTOMA WHO II:

DIFFUSE ASTROCITOMA OLIGODENDROGLIOMA OLIGO-ASTROCYTOMA

Low Grade High Grade

WHO III:

ANAPLASTIC ASTROCYTOMA ANAPLASTIC OLIGODENDROGLIOMA WHO IV: GLIOBLASTOMA MULTIFORME

MGMT, IDH-1

Moving to biomolecular classification