ESTRO PT 2018

Proton beam radiotherapy as part of comprehensive regional nodal irradiation for locally advanced breast cancer.

Verma V 1 , Iftekaruddin Z 2 , Badar N 2 , Hartsell W 2 , Han-Chih Chang J 2 , Gondi V 2 , Pankuch M 2 , Gao M 2 , Schmidt S 2 , Kaplan D 2 , McGee L 3 . Chicago Northwest Proton Center Radiother Oncol. 2017 May;123(2):294-298.

▪ 91 patient treated with adjuvant proton therapy (PBT) targeting the intact breast/chest wall and comprehensive regional nodes including the axilla, supraclavicular fossa, and internal mammary lymph nodes. ▪ Median PBT dose 50.4 Gy (RBE) - subsequent boost as clinically

indicated (N=61, median 10 Gy(RBE)). ▪ Median follow-up time of 15.5 months,

▪ Grades 1, 2, and 3 dermatitis in 23%, 72%, and 5% ▪ Median time to resolution of dermatitis was 32 days.

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