ESTRO PT 2018

Patient Centered Outcomes Research Institut e

PCORI was authorized by the Patient Protection and Affordable Care Act of 2010 as a nonprofit, nongovernmental organization.

PCORI seeks to fund pragmatic clinical trials (PCTs), large simple trials (LSTs), or large-scale observational studies that compare two or more alternatives for addressing prevention, diagnosis, treatment, or management of a disease or symptom;

Funding Cycle – start 2015: Maximum Project Budget (Direct Costs)

$10 million $ 90 million

Maximum Budget

• ……. Particle beam therapy for patients with lung , breast, and prostate cancer: Compare the use of particle beam radiation therapy with other forms of radiation therapies in patients with lung, breast, or prostate cancer. Short- and long-term outcomes of interest might include tumor site–specific toxicities, severity of adverse effects, cancer-specific and overall mortality, quality of life, and functional outcomes. IV. Appendix: Research Topics of Interest to PCORI