ESTRO course on Image Guided Radiotherapy in Clinical Practice 2018

Radiotherapy in breast cancer: Heart Toxicity

Latency of 15-20 years

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• Myocardial scintigraphy can detect perfusion changes as early as 6 mo

Target structures: • Myocardium (e.g. left ventricle) • Vessels (e.g. left anterior descending coronary artery)

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Toxicity • Myocardial infarction • Angina • CHF • Valvular disorders • Electrical conductivity alterations

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Dose threshold??

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03/01/13