ESTRO meets Asia 2024 - Abstract Book

S171

Interdisciplinary – Head & neck

ESTRO meets Asia 2024

Oral Carcinoma patients with positive cervical nodes and Extracapsular Extension: A Real-world data

Rohit Avinash Vadgaonkar 1 , Sonali Susmita Nayak 2 , Sasi Krishna Kavutarapu 3 , Anupurva Dutta 2 , Nageswarrao NOOTHANAPATI 3 , Neeharika Alapatti 4 , Sneha Nachu 1 , Varsha Ramesh Bandal 1 , Pankaj Chauhan 5 , Chandrasekhar Pusarala 1 , Chandrasekhar Dravid 3 , Vidya Viswanath 6 , Raviteja Miriyala 1 , Umesh Mahantshetty 1 1 DEPARTMENT OF RADIATION ONCOLOGY, HOMI BHABHA CANCER HOSPITAL & RESEARCH CENTRE, VISHAKHAPATNAM, India. 2 DEPARTMENT OF PATHOLOGY, HOMI BHABHA CANCER HOSPITAL & RESEARCH CENTRE, VISHAKHAPATNAM, India. 3 DEPARTMENT OF SURGICAL ONCOLOGY, HOMI BHABHA CANCER HOSPITAL & RESEARCH CENTRE, VISHAKHAPATNAM, India. 4 DEPARTMENT OF MEDICAL ONCOLOGY, HOMI BHABHA CANCER HOSPITAL & RESEARCH CENTRE, VISHAKHAPATNAM, India. 5 DEPARTMENT OF DENTAL AND PROSTHETICS SURGERY, HOMI BHABHA CANCER HOSPITAL & RESEARCH CENTRE, VISHAKHAPATNAM, India. 6 DEPARTMENT OF PALLIATIVE ONCOLOGY, HOMI BHABHA CANCER HOSPITAL & RESEARCH CENTRE, VISHAKHAPATNAM, India

Purpose/Objective:

The study aims to assess the topographical distribution, failure patterns, and prognostic factors influencing the outcomes of patients with Oral Squamous Cell Carcinoma (OSCC) having positive cervical nodes with extracapsular extension (ECE).

Material/Methods:

This is a single institute experience of consecutive OSCC patients having pathologically positive cervical nodes with ECE treated with a curative intent between January 1, 2018, to December 31, 2022. Data were extracted from available electronic medical records, and treatment summaries.

Results:

Among the 606 patients with OSCC who underwent curative surgery during the study period, 298 (49.2%) showed cervical lymph nodal positivity, with 142 (47.7%) exhibiting ECE. The median age of the cohort was 49 years and men comprised 113 (79.6%) of total. Primary tumor sites were distributed as buccal mucosa/gingiva-buccal sulcus/retromolar trigone (group 1): 74 (52.1%), oral tongue and floor of mouth (group 2): 59 (41.5%), and hard palate (group 3): 9 (6.3%). The most common surgical procedures for primary comprised composite resection in 69 (48.6%). Bilateral neck dissection (BND) was performed in 68 (47.9%) and unilateral (UND) in 74 (52.1%). Except for two patients, all had negative microscopic margins.