ESTRO meets Asia 2024 - Abstract Book

S174

Interdisciplinary – Head & neck

ESTRO meets Asia 2024

66% of adjuvant patients had local/distant recurrence and 58.3% of definitive patients had local/distant recurrence.

In the adjuvant group, the local recurrence rate is 29% and the distant recurrence rate is 37.4%, compared to definitive group at 22.2% and 36.1% respectively.

Conclusion:

This study provides real world United Kingdom data on survival outcome and recurrence patterns of LA-OCSCC treated with curative intent.

The rate of recurrence is highest in the first two years after diagnosis. Distant recurrence in LA-OCSCC can happen without prior local-regional recurrence. Clinicians should review follow-up strategy to avoid missing distant recurrence. In conclusion, the oncological standard of care for surgically resectable LA-OCSCC patients is primary radical surgery followed by adjuvant (chemo)-radiotherapy as this improves survival outcome. The pattern of recurrence of LA-OCSCC is aggressive and without curative surgery the rate of survival is poorer.

Keywords: Oral cavity squamous cell cancer

References:

1) Keam B, Machiels JP, Kim HR, et al. Pan-Asian adaptation of the EHNS-ESMO-ESTRO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with squamous cell carcinoma of the head and neck. ESMO Open . 2021;6(6):100309. doi:10.1016/j.esmoop.2021.100309

2) Zanoni DK, Montero PH, Migliacci JC, et al. Survival outcomes after treatment of cancer of the oral cavity (1985 2015). Oral Oncol . 2019;90:115-121. doi:10.1016/j.oraloncology.2019.02.001

3) Katsoulakis E, Leeman JE, Lok BH, et al. Long-term outcomes in oral cavity squamous cell carcinoma with adjuvant and salvage radiotherapy after surgery. Laryngoscope . 2018;128(11):2539-2545. doi:10.1002/lary.27191

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Digital Poster

TCTR20230627002: Feasibility of hydrogen gas inhalation in chemoradiation for head and neck cancer

IMJAI CHITAPANARUX 1 , Wimrak Onchan 1 , Somvilai Chakrabandhu 1 , Pooriwat Muangwong 1 , Narongchai Autsavapromporn 1 , Tapanat Ariyanon 2 1 Radiology, Chiang Mai University, Chiang Mai, Thailand. 2 Otolaryngology, Chiang Mai University, Chiang Mai, Thailand

Purpose/Objective: