ESTRO meets Asia 2024 - Abstract Book

S183

Interdisciplinary – Head & neck

ESTRO meets Asia 2024

Material/Methods:

WE ENROLLED 22 BIOPSY PROVEN CASE OF HEAD AND NECK CARCINOMA PATIENTS PLANNED FOR DEFINITIVE RADIATION, FOR THE STUDY. INDIVIDUALS WERE EVALUATED FOR BASELINE UNSTIMULATED SALIVA COLLECTED WITH A CALIBRATED CONTAINER. LATER STARTED WITH CONVENTIONAL TENS THERAPY FROM DAY 1 OF RADIATION, DAILY ALONG SIDE RADIATION TILL THE DAY OF COMPLETION. SALIVA ESTIMATION WAS DONE BEFORE AND AFTER TENS. DURATION OF TENS WAS FOR 10 MINUTES. BOTH THE PAROTIDS AND SUBMANDIBULAR GLANDS WERE ADDRESSED.

Results:

THE SALIVARY FLOW MEASUREMENT WAS MAINTAINED THROUGHOUT THE TREATMENT PERIOD IN ALL THE PATIENTS. MEDIAN FOLLOWUP WAS FOR 10 MONTHS. 18 OUT OF 22 PATIENTS WERE ABLE TO MAINTAIN 90 % THEIR SALIVARY FLOW IN COMPARISON WITH THEIR OWN PRERADIATION BASELINE LIMIT.

Conclusion:

THE ELECTRICAL STIMULATION OF MAJOR SALIVARY GLANDS WITH TENS CAN BE ONE EFFECTIVE ECONOMICAL MODALITY TO INCREASE THE SALIVARY FLOW AMONG THE RADIATION THERAPY PATIENTS TO PREVENT ACUTE AND LATE SIDE EFEFCTS OF XEROSTOMIA. HOWEVER LONG FOLLOWUP AND LARGER STUDIES COULD THROW MORE LIGHT.

Keywords: Xerostomia, TENS therapy, Reactions

300

Digital Poster

Association of lymphovascular invasion with tumor biology and clinical outcome in oral cavity cancer

Dr Simran, Dr Siddhartha Nanda, Dr Papuji Meher, Manish K. Ahirwar

Radiation Oncology, All India Institute of Medical Sciences (AIIMS), Raipur, Raipur, India; Government Medical College, Bhopal, India

Purpose/Objective:

Oral cavity squamous cell carcinoma (OSCC) is the most common oral malignancy, representing 90% of all malignant neoplasms of the oral cavity. Numerous studies have demonstrated that tumor size, histological differentiation, nodal stage and perineural invasion can predict recurrence and survival in patients with OSCC. However, representing an important step in tumor progression toward regional and distant metastasis, the impact of lymphovascular invasion(LVI) on prognosis and survival has not yet been fully clarified. The aim of this study was to examine the associations of LVI with other clinicopathological manifestations, such as tumor size, nodal status, tumor grade, depth of invasion(DOI), perineural invasion(PNI), extranodal extension(ENE) and the patterns of recurrence after OSCC treatment who were treated by surgical resection as the primary modality with or without the use of adjuvant treatment.