ESTRO meets Asia 2024 - Abstract Book

S283

Interdisciplinary – Urology

ESTRO meets Asia 2024

V50Gy=32.6%

V60Gy= 13.2%

Rectum

V30Gy=81.4%

V45Gy=50.5%

V50Gy=40%

V60Gy= 24.5%

Bowel bag

V40 Gy = 323.8 cc

Penile bulb

V40Gy= 55.25 %

Table 1: Table showing the mean doses of various organs at risk

Figure 1 : Dose distribution showing 95% of 68Gy to the prostate planning target volume

Conclusion:

Our study demonstrated encouraging outcomes in prostate cancer patients treated with hypofractionated irradiation of pelvic nodes by simultaneous integrated boost, showing positive results in terms of toxicity and efficacy. This hypofractionated schedule utilizing the low alpha/beta ratio of prostate, enables an expedited completion of radiation treatment. Further validation through longer follow-up periods and a larger sample size is crucial to establish the effectiveness of this radiation strategy.

Keywords: Prostate, Hypofractionation, SIB

References:

1. Dearnaley D, Syndikus I, Mossop H, Khoo V, Birtle A, Bloomfield D, Graham J, Kirkbride P, Logue J, Malik Z, Money Kyrle J. Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5 year outcomes of the randomised, non-inferiority, phase 3 CHHiP trial. The Lancet Oncology. 2016 Aug 1;17(8):1047-60.