ESTRO meets Asia 2024 - Abstract Book

S285

Interdisciplinary – Urology

ESTRO meets Asia 2024

noted in 2/29 [6.89%], 0/29 [0%] and 11/29 [37.93%] patients respectively, with lymphocytopenia being the most frequent grade 3 haematological toxicity and diarrhoea was the only toxicity which required treatment interruption. Moreover, acute toxicities were not significantly correlated with baseline characteristics such as use of systemic treatment and comorbidities, using chi-square test. There was significant PSA decline post-radiation compared to pre-radiotherapy values, evaluated using Wilcoxon signed rank test [p value<0.001].

Conclusion:

Moderately hypo-fractionated EFRT in node-positive prostate cancer is possible with VMAT. However, extended follow-up and larger sample size are required for additional validation.

Keywords: node, radiation, cancer

References:

1. Lépinoy A, Cochet A, Cueff A, Cormier L, Martin E, Maingon P, et al. Pattern of occult nodal relapse diagnosed with 18F-fluoro-choline PET/CT in prostate cancer patients with biochemical failure after prostate-only radiotherapy. Radiother Oncol. 2014; 111[1]:120-5.

2. Pilepich MV, Krall JM, Johnson RJ, Sause WT, Perez CA, Zinninger M, et al. Extended field [periaortic] irradiation in carcinoma of the prostate—analysis of RTOG 75-06. Int J Radiat Oncol Biol Phys. 1986; 12[3]:345-51.