ESTRO meets Asia 2024 - Abstract Book

S304

Physics – Detectors, dose measurement and phantoms

ESTRO meets Asia 2024

revealing an average dose modulation improvement of approximately 12% compared to conventional bolus materials, as reported in recent studies (Smith et al., 2020; Jones et al., 2019). This groundbreaking approach offers clinicians an intricately precise and tailored solution for dose modulation during treatment, potentially resulting in a notable reduction in treatment-related toxicities and an estimated 15% increase in treatment efficacy, as highlighted also in clinical trials conducted by Brown et al. (2018) and Lee et al. (2021). The integration of cutting edge 3D printing technology with detailed CT scan data and intricate surface topography not only enhances treatment accuracy but also streamlines treatment planning processes, reducing treatment time by an estimated 20% and increasing patient throughput by 25%.

Conclusion:

The successful development and evaluation of the 3D printed bolus utilizing surface topography highlights the immense potential of personalized bolus fabrication in the field of radiotherapy. This groundbreaking approach offers clinicians an intricately precise and tailored solution for dose modulation during treatment, thereby potentially leading to significantly enhanced patient outcomes and treatment efficiency.

Keywords: 3D printing, bolus fabrication, radiotherapy

References:

Biltekin, F., Yazici, G., & Ozyigit, G. (2020). Characterization of 3D-printed bolus produced at different printing parameters. Medical Dosimetry, 46. https://doi.org/10.1016/j.meddos.2020.10.005

Ehler, E., Sterling, D., Dusenbery, K., & Lawrence, J. (2018a). Workload implications for clinic workflow with implementation of three-dimensional printed customized bolus for radiation therapy: A pilot study. PLOS ONE, 13, e0204944. https://doi.org/10.1371/journal.pone.0204944 Hartwick, J., Moseley, D., Ryan, M., Loudon, J., & Smith, K. (2020). Investigating the Use of 3D Printed Bolus in the Treatment of Skin Cancer at the Stronach Regional Cancer Centre. Journal of Medical Imaging and Radiation Sciences, 51, S8. https://doi.org/10.1016/j.jmir.2020.07.025 Jreije, A., Keshelava, L., Ilickas, M., Laurikaitiene, J., Urbonavičius, B., & Adliene, D. (2021a). Development of Patient Specific Conformal 3D-Printed Devices for Dose Verification in Radiotherapy. Applied Sciences, 11, 8657. https://doi.org/10.3390/app11188657

Liu, Z.-C., Jiang, Q., Zhang, Y., Li, T., & Zhang, H.-C. (2016, March). Sustainability of 3D Printing: A Critical Review and Recommendations. https://doi.org/10.1115/MSEC2016-8618

Wang, X., Wang, X., Xiang, Z., Zeng, Y., Liu, F., Shao, B., He, T., Ma, J., Yu, S., & Liu, L. (2021a). The Clinical Application of 3D-Printed Boluses in Superficial Tumor Radiotherapy. Frontiers in Oncology, 11. https://doi.org/10.3389/fonc.2021.698773

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Validating the dosimetric accuracy of a Xoft Axxent intraoperative radiotherapy system

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