ESTRO meets Asia 2024 - Abstract Book

S66

Interdisciplinary – Brachytherapy

ESTRO meets Asia 2024

7. Rosenblatt E, Jones G, Sur RK, et al. Adding external beam to intraluminal brachytherapy improves palliation in obstructive squamous cell oesophageal cancer: a prospective multi-center randomized trial of the International Atomic Energy Agency. Radiother Oncol. 2010;97:488–494 8. Rupinski M, Zagorowicz E, Regula J, et al. Randomized comparison of three palliative regimens including brachytherapy, photodynamic therapy, and APC in patients with malignant dysphagia (CONSORT 1a) (Revised II) Am J Gastroenterol. 2011;106:1612–1620 9. Bergquist H, Wenger U, Johnsson E, et al. Stent insertion or endoluminal brachytherapy as palliation of patients with advanced cancer of the esophagus and gastroesophageal junction. Results of a randomized, controlled clinical trial. Dis Esophagus. 2005;18:131–139 10. Gaspar LE, Nag S, Herskovic A, et al. American Brachytherapy Society (ABS) consensus guidelines for brachytherapy of esophageal cancer. Clinical Research Committee, American Brachytherapy Society, Philadelphia, PA. Int J Radiat Oncol Biol Phys. 1997;38:127–132.

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Digital Poster

Comparative Analysis of Dysphagia Relief with EBRT Vs EBRT f/b ILRT in Advanced Esophageal Cancer

Dr Shreya Jain, Dr Ashutosh Mukherji

Radiation oncology, Tata Medical college, Varnasi, India

Purpose/Objective:

To compare dysphagia relief (change in grade of dysphagia) in radiation naïve oesophageal cancer patients with high-grade dysphagia.

Material/Methods:

We performed a prospective study of patients with metastasized or otherwise incurable oesophageal cancer requiring palliation of dysphagia from May 2023 to March 2024. Patients were treated with EBRT in ten fractions of 3 Gy each (total dose 30 Gy). Data was compared with patients treated with EBRT 12 Gy /3 fractions followed by intraluminal brachytherapy dose of 6 Gy x 2 fractions

Results:

Results: Between May 2023 to February 2024, a total of 18 patients were studied of whom 8 were taken in EBRT arm and 10 in ILRT arm. Pre-treatment median dysphagia score for EBRT arm was 3.5 and ILRT arm 3 [ p < 0.32]. At 1 month post treatment, median dysphagia score for EBRT arm was 2.5 and ILRT arm 1.5 [ p< 0.01].

Conclusion:

EBRT followed by ILRT is seen to be more effective in dysphagia relief compared to EBRT only arm. The studied cases are still under follow up for reviewing change if any in dysphagia patterns at longer follow ups.