Gynae BT 2017

Adverse effects  Arm A - More Grade 3-4 toxicities (p<0.001)

 Haematologic Toxicity

 Grade 3-4 ; 71.9% vs 23.9 %

 Non haematologic toxicities

 Vomiting & diarrhea more in arm A (p=0.002)

 Hospitalization during treatment

 Arm A -30 pts & Arm B -11 pts (p=0.02)

 3 deaths in arm A – 2 due to sepsis and bowel perforation & 1 due to

acute encephalopathy

 Late toxicities slightly higher in Arm A

– Grade 4 GI : 2.3 % Vs 0%

GUSTAVE ROUSSY

THÈME DU DIAPORAMA