Gynae BT 2017

Molecular analysis PORTEC-1 and 2 cohort (N=834)

The 4 TCGA subgroups by surrogate markers

Distant metastasis

Overall survival

Locoregional recurrence N SM P

M S I

p 5 3

L E

1 .0

1 .0

1 .0

P - v a lu e < 0 .0 01

P - v a lu e < 0 .0 01

P - v a lu e < 0 .0 01

p 5 3

M S I

P O L E

N SM P

0 .5

0 .5

0 .5

O ve ra ll S u rv iva l

C um u la tiv e p ro b a b ility o f d is ta n t re c u rre n c e

0 .0

0 .0

0 .0

0

5

1 0

0

5

1 0

0

5

1 0

T im e ( y e a rs )

T im e ( y e a rs )

T im e ( y e a rs )

N SM P

M S I

p 5 3

N SM P

M S I

N SM P p 5 3

M S I

p 5 3

P O L E

P O L E

1 .0

1 .0

P - v a lu e < 0 .0 01

P - v a lu e < 0 .0 01

P - v a lu e < 0 .0 01

e n c e

e n c e

ility o f

ility o f