Haematology 2018

In situ vaccination with a TLR9 agonist induces systemic lymphoma response

• 15 patients with r/r iNHL • CpG + low-dose RT single site of disease • Response assessment at distant sites • Treatment induced CD8+ memory T cells and Treg expansion in some patients • Best response in Tregs non inducers

JD Brody, J Clin Oncol 2010;28(28):4324-4332