Haematology 2018

Conclusions CVD after HL (literature and Dutch HL cohort) • After mediastinal RT increased riks of coronary events, valvular disease, CHF

• After 40 yrs: risk of any CVD after mediastinal RT = 50% vs 26% (no mediastinal RT)

• Risk remains increased ≥ 40 yrs

• Younger age at RT → higher risk

• Additive effects of RT and anthracyclines on CHF risk