Haematology 2018

HD10: Second Neoplasia

4ABVD+30Gy

4ABVD+20Gy

2ABVD+30Gy

2ABVD+20Gy

0.5

10-year estimate [95%-CI]

0.4

4ABVD+30Gy 8.4% [4.6% to 12.3%] 4ABVD+20Gy 6.3% [2.8% to 9.8%] 2ABVD+30Gy 7.5% [3.7% to 11.3%] 2ABVD+20Gy 8.9% [4.8% to 13.0%]

0.3

0.2

Median observation time 98 months

0.1

Cumulative incidence +/- 95%-CI

0.0

0 12 24 36 48 60 72 84 96 108 120 132 144 156 168 180

Time [months]

Pts. at risk

298 298 295 299

233 228 231 222

93 86 83 88

15

5

11

6

→ No difference in SIR for any SN: A= 2.1, B= 1.5, C= 1.6, D= 2.1 compared to the age- and sex-specific incidence in the German general population

Bröckelmann et al; EHA 2016