Haematology 2018

HD11: Second neoplasias

ABVD+30Gy

ABVD+20Gy

BEACOPP+30Gy

BEACOPP+20Gy

0.3

10-year estimate [95%-CI] ABVD+30Gy 5.8% [2.7% to 9.0%] ABVD+20Gy 6.5% [3.7% to 9.3%] Bbas+30Gy 6.7% [3.7% to 9.7%] Bbas+20Gy 5.4% [2.5% to 8.3%] Median observation time 106 months

0.2

0.1

Cumulative incidence +/- 95%-CI

0.0

0 12 24 36 48 60 72 84 96 108 120 132 144 156 168 180

Time [months]

Pts. at risk

356 347 341 351

285 281 273 279

113

14 12 16 16

99

124 124

→ No difference in the SIR: A= 1.4, B= 2.4, C= 2.2, D= 1.7 compared to the age- and sex-specific incidence in the German general population

Bröckelmann et al; EHA 2016