Haematology 2018

T-cell counts over time

CD3 + CD4+

Bendamustine

CHOP

CVP

CD3+CD4+ (cells/µl)

Horizontal grey lines = upper and lower limit of normal

BL

BL

BL

C

EOI

EOI

EOI

C1/C2 1/C2

Mo 18

Mo 30

Mo 36

Mo 18 Mo 18

Mo 30 Mo 30

Mo 36 Mo 36

Mo 18

Mo 30

Mo 36

C4/C5

C1/C2

C4/C5

C1/C2

C4/C5

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CD3 + CD8+

Bendamustine

CHOP

CVP

CD3+CD4+ (cells/µl)

BL

BL

BL

EOI

EOI

EOI

Mo 18

Mo 30

Mo 36

Mo 18 Mo 18

Mo 30 Mo 30

Mo 36 Mo 36

Mo 18

Mo 30

Mo 36

C4/C5

C4/C5

C4/C5

C1/C2

C1/C2

C1/C2

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R-benda, n=341

G-benda, n=345

R-CHOP, n=203

G-CHOP, n=196

R-CVP, n=57

G-CVP, n=60

Low T-cell count at baseline

CD3+/CD4+ cell count of ≤200/mm 3

36 (12.5%)

36 (11.4%)

12 (7.2%)

9 (5.1%)

2 (4.4%)

4 (7.4%)

Hiddemann W, et al. Haematologica 2017; 102:314. Abstract S775. Oral communication presented at EHA 2017