Haematology 2018

SWOG Contributions: Limited Stage DLBCL

Risk Factors Age >60

• SWOG 8736 – Established CHOP x 3+RT as standard of care – Introduced the stage-adjusted IPI :

Increased LDH Stage II or IIE ECOG Performance Status ≥ 2

Estimated 5-yr OS in S8736 By Risk Factors 0-1 82% (95%CI 77-87%) 2 71% (95%CI 60-83%) 3 48% (95%CI 22-69%) 4 0%

(Miller, NEJM 1998)