Hematological Malignancies

Chemotherapy of malignant lymphoma

• Development of multi-agent chemo led to cure in lymphoma patients • Most frequently used today are CHOP, ABVD and BEACOPP • Typical side effects include alopecia, aplasia, infection, neuropathy, fatigue and infertility • Major long-term effects are 2 nd neoplasia and organ failure • Prognosis of pts much worse at relapse (DLBCL, HL) • New less toxic drugs have become available and might improve the long-term prognosis