Hematological Malignancies

Choice of radioisotope

90 Yttrium 64 hours Beta (2.3 MeV)

131 Iodine

Properties

Half-life

192 hours

Gamma (0.36 MeV) Beta (0.6 MeV)

Energy emitter

131 I

Path length

5 mm

0.8 mm

χ 90

χ 90

Extensive/variable 46 - 90% in 2 days Clearance based dosing using whole body dosimetry Inpatient or restrictions to protect family/public

Urinary excretion

Minimal 7% in 7 days Based on weight and platelet count

Dosing

Administration

Outpatient