Hematological Malignancies

RT in PCNSL: Dose • Consolidation dose after MRI-CR to chemotherapy: 23.4 Gy in 1.8 Dose per fraction. (13 treatments) • WBRT after incomplete response to chemotherapy: 36 Gy to 45 Gy (1.5 to 1.8 Gy/fraction) • WBRT for salvage of chemotherapy failure (progression or relapse) 36 – 40 Gy (1.5 Gy-1.8 Gy/fraction) • WBRT as primary treatment for non-candidates for chemotherapy: 40-50 Gy • Whole orbit (if included)- only up to 36 Gy • For palliation : WBRT dose is 30-36 Gy in 10 or 15 fractions.