Hematological Malignancies

Risks of Second Malignancy following HL combined results from 3 large studies* (n=9618)

Site or Type

Obs 747 519 155 115

SIR

AER

All SMN

3.8 2.8 4.3 2.4 2.8 2.7 9.2

62.2 37.9 13.4

Solid tumors

Lung

GI tract Stomach

7.0 2.1

29 76 14

Female breast

13.2

Thyroid

1.4

Leukemia

116

22.3 94.8

12.5 14.9

ANLL

63

SIR: Standardized Incidence Ratio; AER: Absolute Excess Risk per 10,000 persons/year *Based on Hancock 1996; Van Leeuwen 2000; Swerdlow 2000