Hematological Malignancies

Internal target volume (ITV) (ICRU 83)

• Defined in ICRU 62, optional in ICRU 83 • CTV + margin for uncertainties in size, shape, and position of the CTV • Mostly relevant when the target is moving (chest and upper abdomen) • Margins may be obtained from 4-D CT, fluoroscopy or from expert clinician • Margins should be added quadratically:

Equation for right-angled triangle