Hematological Malignancies

Splenic Involvement

SIZE: • Wide range of size (race, body size and height) • Normal size spleen may contain lymphoma and enlarged spleen may be due to other causes • No agreement on: – Single, multiple or volumetric measurement – Cut-off

Recommendations for splenic evaluation: • PET/CT: Best method (diffuse, focal) • CT: cut-off for splenomegaly is 13cm vertical length