Hematological Malignancies

GELA LNH-98.5: Trial design

R A N D O M I S

8 x R-CHOP

• Untreated DLBCL • Aged > 60 years

8 x CHOP

E D Cyclophosphamide 750 mg/m² Doxorubicin 50 mg/m² Vincristine 1.4 mg/m² Prednisone 40 mg/m²/day x 5 days R-CHOP: Rituximab 375 mg/m 2 Day 1 of each cycle Cycles every 21 days CHOP:

Coiffier B, et al. Blood 2010; 116:2040–2045.