ICHNO-ECHNO 2022 - Abstract Book

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ICHNO-ECHNO 2022

our study do not show a correlation between the thyroid doses and the occurrence of hypothyroidism. This is probably related to the high doses received by the thyroid in our series. These findings encourage more optimization to limit thyroid doses and then the risk of radiation-induced hypothyroidism.

PO-0158 Quality of life for head and neck cancer patients using EORTC QLQ-H&N35

H. chahdoura 1 , A. Mousli 2 , R. Abidi 3 , K. Mahjoubi 4 , C. Nasr 2

1 Institut Salah Azaiez, Radiation oncology , Tunis, Tunisia; 2 Institut Salah Azaiez, Radiation oncology, Tunis, Tunisia; 3 Institut Salah Azaiez, Radiation Oncology, Tunis, Tunisia; 4 Institut Salah Aziaez, Radiation oncology , tunis, Tunisia Purpose or Objective The aim of our study is to evaluate the quality of life in patients with head and neck (H&N) cancer undergoing radiotherapy in the department of Salah Azaiez Institute. Materials and Methods All patients with head and neck cancer treated with radiotherapy between September and October 2021 were included in our project. The patient’s quality of life was assessed by the EORTC QLQ-H&N35 of the European Organization for Research and Treatment of Cancer. Results Thirty patients were enrolled. The mean age of 55.32± 14.38 years with a sex ratio of 3.4. Sixty percent of patients were treated for nasopharyngeal carcinoma. Among participants, 78% of patients were treated by Intensity-modulated Radiation Therapy (IMRT) and 22% by two-dimensional technique (2DRT). seventy percent of patients received conconmitant radiotherapy and chemotherapy . On the analysis of quality of life, we evaluate the 7 variables: pain, swallowing, sense of taste and smell, Speech, social eating, social contact and sexuality. The highest score was observed with the domains: sense of taste and smell and saliva. About 50% of patients suffered from dry mouth and sticky saliva. A positive correlation was found between the questionnaire for the patient's overall quality of life and the domains: Pain, swallowing, speech social eating social contact and sexuality. Indeed, in univariate analysis, a significant relationship was observed between toxicities prevalence and grade with the number of treatment weeks (fig1). Quality of life was found to be associated with patient age (with patients <65 years obtaining better scores), the stage of cancer, the concomitant chemotherapy and RT technique.

Conclusion Patient-reported quality of life in cancer patients is becoming increasingly important, especially for head-and-neck cancers, which are at risk of severe treatment related toxicities. It also provides a valuable tool for the assessment of health-related quality of life in clinical studies of H&N cancer patients during, and after treatment with radiotherapy.

PO-0159 Transfusing anaemic patients with oropharynx cancer during radiotherapy – are we too cautious?

J. Price 1 , H. Mistry 2 , D. Thomson 1 , C. West 2

1 The Christie NHS Foundation Trust, Clinical Oncology, Manchester, United Kingdom; 2 The University of Manchester, Division of Cancer Sciences, Manchester, United Kingdom