ICHNO-ECHNO 2022 - Abstract Book

S110

ICHNO-ECHNO 2022

Results The study included 22 PTC patients who had undergone lymph node dissections. Patients had a median age of 38.8 years (IQR = 32.2–54.5), and the median tumor size was 20.5 mm. The most commonly affected level of the neck was IV (76.2%). Distant metastasis M1 was seen in only two patients (9.1%). Tumors sizes >30mm (75%) had ≥ 5 LNM. Most cases were the classic subtype PTC. For the site of the tumor, the site had a significant impact on the number of LNM (p = 0.004). Multifocality had a high impact on LNM (p = 0.019). Conclusion This study showed no association between the size of PTC and the number of LNMs. The bilaterality of PTC was significantly associated with a high number of LNMs. J.M. Costa-González 1 , R.D. Ramírez-Ruiz 1 , F.X. Avilés-Jurado 1 , I. Vilaseca-González 1 , P. Mackers 2 , Z. Piñeiro-Aguin 2 , A. Sumarroca 2 1 Hospital Clinic Barcelona, Otorhinolaryngology, Barcelona, Spain; 2 Hospital del Mar Barcelona, Otorhinolaryngology, Barcelona, Spain Purpose or Objective To define the degree of neck lymph node involvement in cutaneous squamous cell carcinomas of the face. To specify the guidelines for cervical neck dissection or parotidectomy. Materials and Methods It is known that the risk of cervical or parotid metastasis in cutaneous squamous cell carcinomas is around 5%, that regional involvement is associated with a worse prognosis and that the majority of lymph node recurrences appear in the first 2 years of follow-up. We retrospectively studied a total of 37 patients with cutaneous squamous cell carcinoma of the face, we treated them surgically, we conducted a 5-year follow-up, and we analyzed their lymph node involvement at diagnosis and their cervical recurrence. Results We staged our patients according to the 8th Edition of the TNM: 27 patients were staged pT1, 5 were staged pT2, 3 patients were staged pT3 and 2 patients were staged pT4. We studied the majority of patients with a cervical CT scan, however, 26 patients were staged cN0, 3 patients had lymph node involvement at diagnosis (8% pN+), and 8 pT1 patients were staged Nx . All patients with lymph node involvement (3/37) underwent unilateral neck dissection (areas I-II-III). In case of tumor anterior to the ear pavilion, a suprafacial parotidectomy was also performed, and in case of posterior tumor, areas IV and V were treated. None of these patients developed lymph node recurrence. 24% of patients (9/37) had cervical lymph node recurrence, all in patients initially classified as cN0 (3/9, 33%) or cNx (6/9, 67%). 6 of 9 patients with recurrence died due to the disease. Conclusion Most of head and neck cutaneous squamous cell carcinoma are high risk. Although lymph node involvement at diagnosis is relatively low, it is important to perform a neck study (CT scan for example) in the initial assessment and follow the patient closely to detect cervical metastases and to be able to treat the neck with good results before the disease progresses. Purpose or Objective Prospective data is lacking regarding the potential benefit of the addition of chemotherapy in the adjuvant treatment of salivary gland malignancies, with results from the recently accrued RTOG 1008 randomized trial pending. We sought to retrospectively evaluate whether the addition of concurrent chemotherapy for patients with intermediate to high-grade salivary malignancies provided significant benefits in regards to locoregional control, distant control, and overall survival. Materials and Methods A retrospective analysis of 51 patients with intermediate to high-grade salivary gland malignancies treated with oncologic resection with high-risk pathologic features (T3-T4, node positive, or close/positive margin) followed by adjuvant radiation therapy or chemoradiation therapy at our institution between 2002 and 2016 was performed, with exclusion of patients with limited available data. Median patient age was 63 (interquartile range [IQR] 49-72). Twenty-nine patients (57%) were node-positive. Seventeen patients (33%) received concurrent chemotherapy. Locoregional control, distant control, and overall survival were calculated from date of surgery to date of event, with censorship at last follow-up. Chi-Square test was performed to assess for differences in baseline characteristics based on receipt of chemotherapy. Log-rank test was utilized for univariate analysis of outcomes based on receipt of chemotherapy. Results Median follow-up was 6.3 years (IQR 2.9-8.9 years). Median overall survival was 8.9 years (95% CI 5.4-12.3 years). Median time to locoregional failure was not reached, with 5-year Kaplan-Meier estimate of local control of 78.1%. Median time to PO-0174 Management of the neck in head and neck cutaneous squamous cell carcinoma PO-0175 Long-term outcomes of salivary gland malignancies treated with adjuvant radiation therapy A. Keller 1 , S. Koerner 1 , D. Clump 1 1 UPMC Hillman Cancer Center, Department of Radiation Oncology, Pittsburgh, PA, USA