IMRT 2018

Hypofractionation

• Generally favourable results with moderate and severe hypofractionation

• Urinary toxicity reported to have increased

Rectal toxicity kept low through: • Frequent set-up imaging • Tracking • Adaptive RT? • Allowing heterogeneous target dose? • Rectal spacer?

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Clemente et al, IJROBP vol 91, n1, 182-95, 2015 Cozzarini et al, Eur Urol vol 66, n6, 1024-30, 2014 Ruggieri et al, BJR vol 88, 1054, 2015

06/06/2018