IMRT 2018

… Phase 3 trial RTOG 0415

Non-inferiority comparing two fractionation schedules Moderate HFRT vs SFRT in low risk patients

N: 1115 patients

70 Gy in 28 fractions x 2.5 Gy is not inferior to 73.8 Gy in 41 fractions x 1.8 Gy

5y RFS: 77% vs 80%

Lee, 2016