IMRT 2018

And most recently……

ELIOT (Veronesi, Lancet Oncol, 2013) No significant difference in secondary cancers at median F/U of 5 years

Uppsala Örebrö (Wickberg, JCO, 2014) 5% (contral. Breast cancer) and 2% (any cancer) absolute difference after 20 Years

Prime II (Kunkler et al., SA-Breast Cancer 2013) No signisficant) difference in secondary cancers at median F/U of 5 years (>65Y)