IMRT 2018

Late effects and OAR Dose

Author

Disease

Dose RR

Breast Cancer

≥ 4 Gy 3.2

Travis et al JAMA 2002

Lung Cancer

≥ 5 Gy 5.9

Travis et al JNCI 2003

Thyroid Cancer

≥ 5 Gy 8.5

Bhatti et al Rad Research 2010

Brain tumors

>10 Gy 9.7

Neglia et al JNCI 2006

Gastric Cancer

>20 Gy 9.9

Belt-Dusebout et al IJROBP 2000

Tukenova et al IJROBP 2011

Sarcoma

>150 J 5.0

Carcinoma

>150 J 5.2

Cardiac death

≥ 5 Gy 12.5

Tukenova et al JCO 2012

Mulrooney et al BJH 2009

CHF

≥ 15 Gy 2.2

MI

≥ 15 Gy 2.4

Pericardial

≥ 15 Gy 2.2

Valvular

≥ 15 Gy 3.3