IMRT 2018

Equivalent uniform dose

Note that to apply the LKB model as described, a whole-organ inhomogeneous dose distribution must be converted to a uniform dose, EUD, which has the same likelihood of causing a complication. The parameter n is introduced to represent volume dependence of the organ.

Lung: n = 0.99

Rectum: n = 0.09

100

100

DVH EUD

DVH EUD

80

80

60

60

40

40

Volume (%)

Volume (%)

20

20

0

0

0

20

40

60

80

0

20

40

60

80

Dose (Gy)

Dose (Gy)

05/06/2018