IMRT 2018

Voice Quality

▪ Radiotherapy affects voice quality in locally advanced HN cancer but less so in early-stage larynx cancer

▪ From the published data, it seems reasonable to suggest limiting the mean noninvolved larynx dose to 40–45 Gy and limiting the maximal dose to <63– 66 Gy, if possible, according to the tumor extent.

Rancati T, Schwarz M, Allen AM, Feng F, Popovtzer A, Mittal B, Eisbruch A. Radiation dose-volume effects in the larynx and pharynx. Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S64-9.