IMRT Course 2016

ROC curves for factors predicting local control

Prescription BED 10 highest AUC (0.693; p < 0.001) Optimal cut point of 105 Gy (sensitivity of 81% and specificity of 50%)

2-year LR BED

< 105 Gy 15%

10

BED

10 > 105 Gy 4% (p < 0.001)

Kestin et al, Radiother Oncol 2014