IMRT Course 2016

Treatment of targets with large interfractional deformations: Plan-selection strategies

Example: female pelvis

Bondar et al. 2011 (Rad. Onc. 99(2)); courtesy M. Hoogeman (Erasmus MC)

• ART for cervical cancer: For 90% of pts. with CTV coverage of >=95%…

* non-ART population based CTV-PTV volume 1702 ± 274ml (38mm margin) * online-adaptive 2-plan library: CTV-PTV volume 764 ± 165ml (7mm margin) (Bondar et al. 2012, IJROBP 83(5))

• ART for bladder cancer, online adaptive 3-plan library: compared to non-ART, V 57Gy (Vestergaard et al. 2013, Rad. Onc. 109(3)) and median PTV volume reduction by 30% (Vestergaard et al. 2014, Acta Oncol. 53(8))

of body tissue reduced by 34%

ESTRO IMRT course 2016 Adaptive Radiotherapy London April 7th, 2016

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