IMRT Course 2016

IMRT Retrospective evidence: 2

165 IMRT vs 154 3D-CRT patients Median time to local recurrence 18 months 5 year local recurrence rates: IMRT 7.6% 3D-CRT 15.1% p=0.05 Acute grade 2 skin reaction less with lMRT (48.7% vs 31.5%) Chronic ≥ grade 2 toxicity (fractures, joint stiffness, oedema) no difference

25 Folkert MR et al. Comparison of Local Recurrence With Conventional and Intensity-Modulated Radiation Therapy for Primary Soft-Tissue Sarcomas of the Extremity. J Clin Oncol 2014, 32:3236- 3241