IMRT

Monte Carlo sim. 175

E. Sterpin et al. / Radiotherapy and Oncology 104 (2012) 173–180

Δ (Dp,ptv - Dc,ctv) Interplay

Δ (Dp,ptv - Dc,ctv) Mov. only

Tech.

0.45% (-1.3,2.7)

0.47% (-1.4,2.7)

4DCT-SIB

-0.29% (-2.4,2.1)

4D-PET SIB -0.34% (-1.2, 2.6)

1.19% (-1.5,2.8)

1% (-2,2.8)

SBRT 3x18Gy

of the integration of the 4D MC dose calculation process with beamlet-phase correlation in the overall clinical workflow. Bottom part corresponds to the cific to this study. The top-left part corresponds to the conventional clinical process. The top-right part corresponds to the additional PET-based contouring . D P 3 D denotes the planned dose map computed with TomoPen, D IS 4 D ð i Þ and D NI 4 D ð i Þ the dose computed at phase i with interplay effect simulated or not, (i) the deformation between the phase i and the 3D CT. Finally, D IS 3 D and D NI 3 D denote the computed dose including interplay effect or not, respectively. Sterpin et al., Radiotherap and Oncology 104 (2012) 173–180