IMRT

Is there a genetic component in late rectal bleeding?

The data seem to confirm Cesaretti et al’s findings (in brachytherapy) on the possible genetic component of rectal bleeding

High-dose region: the genetic makeup plays a minor role and the dose the major role

Low-dose region: the genetic makeup might play the major role

When more pts are available, it might be reasonable to unveil the double nature of the dose-response relationship also for external radiation

Courtesy of Riccardo Valdagni, Milan