IMRT

Dominant intraprostatic lesion = cancer-validated areas within the prostate as target for dose escalation

Clinically significant prostate cancer local recurrence after radiation therapy occurs at the site of primary tumor 1,2 Relationship: local control - distant metastasis - survival 3,4

1 Pucar D, et al. IJROBP 2007; 69: 62-69 3 Coen JJ, et al. JCO 2002; 20: 3199-3205

2 Cellini N, et al. IJROBP 2002; 53: 595–599 4 Jacob R, et al. Cancer 2004; 100: 538-543

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