IMRT

Shaikh et al. : “Our analysis finds that helical tomotherapy treatments are generally superior to SMLC and DMLC treatment plans in this aspect due to the relatively rapid dose accumulation seen by a given target volume element.” “… Newer rotational delivery techniques such as VMAT , which are capable of total treatment delivery times shorter than any of the techniques studied here, should be expected to result in similar biological effects to those from helical tomotherapy as presented here.” “If the relationships between treatment time and biological effectiveness were accurately known for clinical situations, one could modify the prescription dose to compensate. Unfortunately, these relationships are not completely understood and depend on factors that are not accurately known (i.e., α / β ratios and repair half-times, etc.)