IMRT

3D vs VMAT-TOMO: LUNG

Rousseau Cancer Radioth 2012

10 pts PTV 723 (392-885 cc) 13 pts PTV: 215- 745

V5: 13% higher VMAT V20: 24 vs 20 (p<0.01) V30: 20 vs 14 (p<0.01) MLD 14 vs 12.2 Gy

Cattaneo Radiot Oncol 2008

Dmean: 20.4 vs 16.8 Gy p=0.001 V5: 67.4 vs 70.4% p= 0.61 V10: 56.4 vs 54.2% p=0.694 V15: 43.1 vs 37.4% p=0.013 V20: 33.5 vs 25.8% p= 0.002 V30: 27 vs 17.5% p=0.001 TOMO: Mean lung dose reduction of 31% (10-53%) Mean V20 reduction of 22% (17-37%)

Scrimger AMJCO 2003

5 pts PTV 169cc (132-280)