IMRT

Frameless vs. Invasive frame-based

Framebased SRS

Frameless IGRT

Positioning error (3D)

0,5 – 1,5 mm

< 1 mm

Intrafractional error (3D)

< 1 mm

< 1,5 mm

Maciunas 1994 Lamba 2009 Ramakrishna 2010

Murphy 2003 Boda-Heggemann 2006 Guckenberger 2007 Lamba 2009 Ramakrishna 2010 Gevaert 2012

Invasive frame-based: Submillimeter accuracy?? Good immobilization Frameless approach: Submillimeter accuracy!!! Immobilization?

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