IMRT

The IMRT optimization problem: What is optimized, and what are the variables?

(Dose target )

CF target

(2) optimize a weighted sum of these CFs by finding an optimal fluence modulation pattern for the beams (1) the treatment/dose goals are expressed in terms of C ost F unction(s) for target and OARs.

The optimization variables may be beamlet weights or segment weights and -shapes => depending on the case, in the order of 10 3 -10 4 variables!

(Dose OAR )

CF OAR

ESTRO IMRT course 2015 IMRT optimization: algorithms&cost functions Brussels October 5th, 2015

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