IMRT

Parametrisation of the Solution Space by Weight Factors

Problems with manual weight adjustments: goals and weight factors are not inversely proportional changing one weight factor affects all other goals Weight factors make the solution space accessible, but are not well suited for exploring it during the search for the best balance between goals.

(

) G F L λ

−+ = 1

λ

1/8

target goal F

2/8

4/8

3/8

5/8

6/8

7/8

normal tissue goal G

ESTRO IMRT course 2015 IMRT optimization: algorithms&cost functions Brussels October 5th, 2015

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