IMRT

„Automated planning“

Automatic choice of the „optimal“ pareto-optimal plan!

Basic idea/aim: Automatically find a patient-specific set of CF-prescriptions/constraints as starting point of an IMRT optimization that will result in the clinically most acceptable plan from the solution space of this patient. How does it work? • Finding: In a population of patients, a similar compromise of PTV coverage vs. dose constraints will be realizable for patients with ‚similar geometry‘ • Use of prior knowledge to predict realizable DVHs/dose presciptions for a new patient • Algorithm based on database of patients/correlation model/machine- learning/... To some extent institution-specific; the larger the ‚input‘ patient- database, the better it works...

ESTRO IMRT course 2015 IMRT optimization: algorithms&cost functions Brussels October 5th, 2015