IMRT
Precise dose computation DURING fluence profile optimization is immensely expensive!
• computation time issue • computer memory issue (10.000 beamlets can be ~Gigabyte memory)
This is why some planning system calculate simplified beamlet doses: too steep and/or truncated penumbra, esp. in presence of inhomogenieties
thus, OARs may wrongly appear sufficiently spared
the final, more precise dose calculation reveals such initial simplifications! → plan degradation of segmented plan!
5 cm!
4 mm x 2 mm beamlet, 15 MV, 3D-PB
ESTRO IMRT course 2015 IMRT optimization: algorithms&cost functions Brussels October 5th, 2015
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